estrangement of his daughter, Grace; and now, a devastating diagnosis. ALS. The relentlessly progressive paralysis of ALS begins in the cruellest way possible - in his hands. As Richard becomes more and more locked inside his body and can no longer play piano or live on his own, Karina steps in as his reluctant caregiver. Paralysed in a different way, Karina is trapped within a prison of excuses and blame, stuck in an unfulfilling life as an after-school piano teacher, afraid to pursue the path she abandoned as a young woman. As Richard's muscles, voice and breath fade, the two struggle to reconcile their past before it's too late. With a strong musical sensibility and the staggering insight of Jojo Moyes' Me Before You, Lisa Genova has delivered a masterful exploration of what it means to find yourself within the most shattering of circumstances.